Deep sea squid and Marine D3 health claims


What Is Marine-D3 and does it live up to anti-aging claims? [See Deep sea Marine D3 supplement for omega oils’ Health Claims]

Answer by ConsumerLab:
Marine-D3 is a supplement sold online by Marine Essentials which claims the product is effective at slowing down or reversing the main causes of aging and disease and will, among other things, reduce fat and increase energy. Unfortunately, no clinical studies have been published to back up these claims specifically for the Marine-D3 formula.

On the Marine-D3 website we were not able to find a list of the product’s ingredients (i.e., its “Supplement Facts”), but a sales representative informed us through online chat that each capsule contains 1,000 IU of vitamin D3, 300 mg of EPA and DHA from calamari oil (Calamarine®), and 40 mg of an extract from brown seaweed (Seanol-P®). Two capsules daily are suggested. Each capsule costs 83 cents ($1.67 daily) based on purchasing four 60-capsule bottles at the “Private VIP” price of $199.80. has not tested this product to determine the amounts and quality of the claimed ingredients. Assuming it delivers what it claims, however, a daily dose of two capsules would provide a substantial 2,000 IU dose of vitamin D3 which could be appropriate for someone moderately deficient in vitamin D and could, for such a person, have a variety of benefits (See Vitamin D Product Review for more about vitamin D). Of course, if you are not deficient in vitamin D, this ingredient may be of no value. It is also important to note that this dose of vitamin D is much higher than the recommended daily intake for adults of 400 IU. Too much vitamin D (over 4,000 IU per day) may have negative effects.

The amount of EPA and DHA from calamari oil claimed in two capsules of Marine-D3 is also substantial — 600 mg. If you are not already eating fish twice a week, there are a range of potential benefits from these omega-3 oils (see Fish Oil and Omega-3 Product Review for more information).

The third ingredient in Marine-D3 is an extract of brown seaweed (an algae known as Ecklonia cava) called Seanol®-P. Many of Marine-D3’s medical claims appear to relate to this ingredient. The extract has anti-oxidant effects and, according to its manufacturer, BotaMedi, has been authorized by the FDA for use as a dietary ingredient. A recent 12-week double-blind, randomized clinical trial of 97 overweight men and women in Korea showed that a daily dose 144 mg of this extract experienced significant improvements in body weight, BMI, body fat ratio, and waist circumference, compared to those who received placebo — although this comparative benefit was not found for those receiving a lower dose of 72 mg. However, both low- and high-dose groups showed significant reductions in total cholesterol and LDL cholesterol and increases in HDL (“good”) cholesterol compared to people receiving placebo, with total cholesterol falling by 14.6 and 18.8 mg/dL in the low- and high-dose groups, respectively (Shin, Phytother Res 2012). The daily dose of Seanol-P in Marine-D3 (80 mg) is similar to the lower dose used in this study, suggesting that Marine-D3 may not reduce body fat but may improve cholesterol levels.

As for Marine-D’s claim that it increases energy, one randomized, placebo-controlled study found that young men drinking a Ecklonia cava preparation before high intensity exercise had an increased time-to-exhaustion — an extra 2 minutes (Oh, Int J Sport Nutr Exerc Metab 2010). This may suggest a benefit for exercise endurance but more studies are needed.

From a cost perspective, you can get the vitamin D3 and omega-3 fatty acids in Marine-D3 from individual supplements at much less cost than the $1.67 per day for Marine-D3. Choosing the best priced, quality-Approved supplements tested by, you can get 2,000 IU of vitamin D3 for as little as 1 cent from liquid drops or (4 cents from a capsule or softgel), and you can get 600 mg of EPA and DHA from calamari oil for 30 cents (or from fish oil for just 6 cents). The bulk of what you are paying for in Marine-D3 is Seanol-P. Seanol is available in several other marketed supplements, although these products use what is called Seanol-F, which is apparently a less concentrated ingredient than Seanol-P. The Seanol-F products are generally targeted at the treatment of fibromyalgia. Nutricology Fibroboost® for example, provides 1,200 mg of Seanol-F per capsule, with each capsule costing around 50 cents.

In short, Marine-D3 appears to be a clinically untested formulation and there is no evidence that it is effective as an “anti-aging” product. Its individual ingredients may offer selected benefits to specific individuals but buying this product means paying a large premium to get vitamin D, omega-3 fatty acids, and relatively new ingredient for which there is only preliminary and limited evidence of potential benefit.


Another article review of the product “A Review of Marine-D3 and Its Ingredients: Can Aging be Reversed?”  says:

Marine-D3 is the product of Marine Essentials LLC, a company that is based in South Carolina and has been in the business of producing supplements and other nutritional products for the past three years. Although it is not as popular as some of the biggest manufacturers and distributors of supplements being marketed nowadays, the company nonetheless has earned a reputation of using only the best ingredients in their supplements and conducting excellent research on various materials that can benefit the body in general.

Aging is a natural bodily occurrence, and with this comes issues that you will surely encounter as you get older. These include high blood pressure, loss of skin elasticity, digestive problems, and poor eyesight. All of these are caused by cell degeneration inside the body wherein free radicals attach themselves to healthy cells and destroy the cellular structure. Marine-D3 aims to reverse the aging process through the use of powerful antioxidants contained in each capsule that can fight these free radicals and stop oxidation from accelerating. The supplement has three main ingredients to boast of, with two of them having been extracted from plants and marine life that thrive in the depths of the ocean. These ingredients have become commonly known in the medical research field as superantioxidants, and for good reason.

The Ingredients in Marine-D3

The first ingredient contained in each bottle of Marine-D3 is Seanol-P, a brown seaweed extract (Eckloma Cava) that is quite rare and cannot be found in just about any type of supplement in the market. It is 7 times more potent than the usual Seanol-F which is included in many anti-aging products and provides protection to the cells for 12 hours. Seanol-P polyphenols are also more efficient than those found in blueberries, green tea, or acai berry.

Comparing Seanol Levels in Marine-D3

The second ingredient used in Marine-D3 also comes from marine life and is called Calamarine. This squid oil extract has been proven to have more Omega-3 and DHA than fish oil – up to 85% more in fact. These two essential fatty acids are known to reduce the risk of heart disease and many other health conditions, not to mention providing better cell functions. Omega-3 and Omega-6 are two of the more popular types of fatty acids known to the public, but the former is known to be more beneficial than the latter.

 What You Get with Marine-D3

You see, the average diet of a person contains high levels of Omega-6 that can be found in leafy vegetables, bakery products, seeds, and the like. However, too much Omega-6 can also cause an imbalance in the body which in turn causes various health problems, and this is where Omega-3 from Calamarine comes into play. It acts to provide balance to the levels of Omega-6 found in the body and prevents these health conditions from cropping up. Calamarine when ingested by cells in body allow for better absorption of Seanol-P, which then strengthens the cells from the inside and makes them less prone to degeneration brought about by free radicals.

Lastly, Marine-D3 contains a pure form of Vitamin D3 or cholecaiferol. This type of vitamin is produced in the skin when it comes into contact with the sun’s rays and helps prevent the onset of various bone, joint, and skin conditions. People who lack the necessary Vitamin D levels are more prone to these types of health issues, and if you don’t get enough exposure to sunlight to create the necessary cholecaiferol, you need to have a supplement that provides you with this nutrient. In the cellular level, this vitamin helps increase immunity and allows for better insulin secretion.

How Marine-D3 Works

Those who plan on taking Marine-D3 are advised to take 2 softgel capsules per day depending on their preferred schedule. I tried the company’s initial offering and started taking one softgel capsule every morning just before I eat breakfast and another one at night before bedtime. I find that this works quite great for me, seeing that I need the additional boost in the morning and allows for the antioxidants in the ingredients to work better during the night while I rest. If you have hectic days or are suffering from too much stress at work, I suggest that you follow the same routine I have been doing so you can get the most of the supplement.

All three ingredients combined provide stronger cells, allowing the body to function more properly – something that becomes gradually lost as years pass because of aging. Seanol-P and Vitamin D3 are better absorbed the body because of Calamarine, and this is what makes cellular structure immune to free radicals and cell degeneration.

Effects of High and Low Levels of Vitamin D

End of Excerpt


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